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. 1986 Feb;6(2):707–709. doi: 10.1128/mcb.6.2.707

Detection of UV purine photoproducts in a defined sequence of human DNA.

P E Gallagher, N J Duker
PMCID: PMC367562  PMID: 3785156

Abstract

The UV-irradiated, 3'-end-labeled, 92-base-pair terminus of the human alphoid sequence was incubated with purified endonuclease v. Previously unreported photoproducts were incised at purine loci. These were not pyrimidine photodimers, 6-4'-(pyrimidin-2'-one)-pyrimidines, base loss sites, or ring-opened purines. Therefore, purine-containing photoproducts, possibly dimers, were incised by the enzyme preparation.

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Selected References

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