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. 1986 Apr;6(4):1357–1361. doi: 10.1128/mcb.6.4.1357

An active chromatin structure acquired by translocated c-myc genes.

E Kakkis, J Prehn, K Calame
PMCID: PMC367653  PMID: 3023885

Abstract

We used general sensitivity to DNase I digestion to analyze the chromatin structure of c-myc genes in seven murine plasmacytomas. In every case, the 3' portion of c-myc juxtaposed with C alpha displayed a much more DNase I-sensitive chromatin structure than untranslocated c-myc or, in one case analyzed, the reciprocally translocated 5' portion. Our data suggest the presence of regulatory sequences near the C alpha gene segment.

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Selected References

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