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. 1986 May;6(5):1838–1842. doi: 10.1128/mcb.6.5.1838

Determination of DNA sequence changes induced by ethyl methanesulfonate in human cells, using a shuttle vector system.

J S Lebkowski, J H Miller, M P Calos
PMCID: PMC367715  PMID: 3023907

Abstract

The DNA sequence changes for 54 mutations induced in human cells by the alkylating agent ethyl methanesulfonate are reported. The mutations were obtained by using a shuttle vector system with the bacterial lacI gene as the target. Of the 54 mutations obtained, 53 were G:C to A:T transitions.

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Selected References

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