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. 1987 Aug;7(8):3004–3007. doi: 10.1128/mcb.7.8.3004

Different early-signaling pathways coupled to transcriptional and posttranscriptional regulation of gene expression during mitogenic activation of T lymphocytes.

M W White 1, A K Oberhauser 1, C A Kuepfer 1, D R Morris 1
PMCID: PMC367924  PMID: 3499567

Abstract

Two categories of mitogen-induced mRNAs were defined in T lymphocytes. The type 1 messages (represented by c-myc) were regulated transcriptionally, and their expression seemed to be calmodulin dependent. The type 2 messages (ornithine decarboxylase, actin, and alpha-tubulin) were regulated posttranscriptionally through activation of protein kinase C.

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Selected References

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