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. 1987 Nov;7(11):4130–4133. doi: 10.1128/mcb.7.11.4130

A complex translocation at the murine kappa light-chain locus.

M A Shapiro 1, M Weigert 1
PMCID: PMC368086  PMID: 3123918

Abstract

We have previously reported that a segment of DNA from a murine plasmacytoma comprises DNA from three chromosomes, the immunoglobulin kappa light-chain locus on chromosome 6, the S mu locus on chromosome 12, and a region on chromosome 15. We now report that the reciprocal product contains DNA from only the kappa locus and chromosome 15 and not from S mu. We conclude that a complex series of events, including both a transposition of DNA and a translocation between chromosomes, generated these imperfect reciprocal products.

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Selected References

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