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. 1987 Dec;7(12):4560–4563. doi: 10.1128/mcb.7.12.4560

Identical genomic footprints of the adenovirus EIIa promoter are detected before and after EIa induction.

B Devaux 1, G Albrecht 1, C Kedinger 1
PMCID: PMC368143  PMID: 2963956

Abstract

Genomic DNase I footprinting was used to compare specific protein binding to the adenovirus type 5 early, EIa-inducible, EIIa promoter. Identical protection patterns of the promoter region were observed whether EIIa transcription was undetectable or fully induced. These results suggest that EIa-mediated transcriptional induction does not increase binding of limiting transcription factors to the promoter but rather that transactivation results from the proper interactions between factors already bound to their cognate sequences.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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