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. Author manuscript; available in PMC: 2013 Jun 17.
Published in final edited form as: Parasitology. 2011 Nov 14;139(1):1–13. doi: 10.1017/S0031182011001673

Table 5.

Histogenesis of lesions of acute toxoplasmosis in transgenic mice fed few ME 49 (Type II) or TgGoatUS26(Atypical) oocysts

Dose Mouse
strain
T.gondii
strain
Day
p.i.
Intestinal segmentsa M.Lb Othersg
1 2 3 4 5 6
100 A.3.11 ME 49 3 -c - - - - - - -
100 A.3.11 ME 49 4 +d - - - + - + -
100 A.3.11 ME 49 5 + + + + ++e - ++ Sp
100 A.3.11 ME 49 6 + + + + ++ + +++ H, Li, Lu, Sp
100 A.3.11 ME 49 7 + + + ++ +++f + +++ H, Li, Lu, P, Sp
100 A.3.11 ME 49 9 + + + ++ +++ + ++ B, H, K, Li, Lu, Sp, T
100 A.3.11 ME 49 10 + + + ++ +++ ++ ++ A, B, H, K, Li, Lu, Sp, T
100 B7 ME 49 8 + ++ ++ ++ +++ ++ ++ B, H, K, Li, Lu, Sp, T
100 B7 ME 49 10 + + + ++ ++ + ++ B, H, K, Li, Lu, M, P, , Sp, T,U
1 B7 ME 49 12 + + + ++ ++ + ++ B,H,K, Li, Lu, M
100 A.3.11 TgGoatUS26 6 + + + ++ +++ + +++ H, Li, Lu, Sp
10 A.3.11 TgGoatUS26 7 + + + ++ +++ + +++ B, K ,Li, Lu, Sp, St
1 A.3.11 TgGoatUS26 10 + + + + ++ - ++ B, H, K, Li, Lu, T
1 A.3.11 TgGoatUS26 11 - + + + + - ++ A, K, Lu, Sp, U
a

1-5. small intestine. 6-large intestine.'

b

Mesenteric lymph nodes.,

c

no lesions, no T. gondii.

d

Few T.gondii, no lesion..

e

Nearly all villi affected or severe lesions.

f

B=brain, E= eye, H= heart, K=kidneys, Li=liver, Lu=lungs, , M=skeletal muscle, P=Pancreas, Sp=spleen,St=stomach, T=tongue, U=uterus