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. 1983 Apr;3(4):750–755. doi: 10.1128/mcb.3.4.750

Identification of the Cloned Gene for the Murine Transplantation Antigen H-2Kb by Hybridization with Synthetic Oligonucleotides

Dan H Schulze 1, Larry R Pease 1, Yuichi Obata 2, Stanley G Nathenson 1, Antonio A Reyes 3, Satoshi Ikuta 3, R Bruce Wallace 3
PMCID: PMC368591  PMID: 6855774

Abstract

The H-2Kb gene is a member of the large major histocompatibility complex class I gene family. Since many members of this family cross-hybridize with class I cDNA probes, the cloned H-2Kb gene was identified by hybridization with specific oligonucleotide probes. This clone was definitively shown to encode the H-2Kb polypeptide by partial DNA sequencing and by serological and tryptic peptide analyses of the expressed product.

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Selected References

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