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. 1983 Jun;3(6):1157–1162. doi: 10.1128/mcb.3.6.1157

Neural tissues express high levels of the cellular src gene product pp60c-src.

P C Cotton, J S Brugge
PMCID: PMC368645  PMID: 6192323

Abstract

Chicken embryo tissues were examined for the expression of pp60c-src, the normal cellular homolog of the transforming protein of Rous sarcoma virus. Three assays, including a solid-phase radioimmunoassay, a competitive radioimmunoprecipitation assay, and an immune complex protein kinase assay, were employed. Elevated levels of pp60c-src were detected in lysates from several neural tissues, including brain, retina, and spinal ganglia. Other tissues contained 8- to 10-fold-lower levels of pp60c-src, levels comparable to those found in chicken embryo fibroblasts. Expression of pp60c-src in brain tissues was also shown to vary with the developmental stage of the embryo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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