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. 1984 Apr;4(4):755–760. doi: 10.1128/mcb.4.4.755

Polyoma middle T antigen requires cooperation from another gene to express the malignant phenotype in vivo.

C Asselin, C Gélinas, P E Branton, M Bastin
PMCID: PMC368794  PMID: 6325896

Abstract

The oncogenic potential of polyomavirus in newborn hamsters can be expressed by a recombinant encoding only the middle T protein. However, polyoma middle T requires the cooperation from small T to induce tumors in newborn rats. Similar complementary functions such as cocarcinogens or tumor promotors can be exerted by the simian virus 40 T antigens as well as by one or several products of the early region 1A of adenovirus 2.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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