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Effect of dutasteride on the expression of various androgen-responsive genes in LuCaP35 tumors 4 days after testosterone implantation. Data shown are qPCR analysis of androgen-responsive genes, calreticulin, EAF2, PSA, and ELL2, in C, C+T, and C+T+D LuCaP35 xenograft tumors. Data were normalized to GAPDH. Number of animals in each group is shown in parentheses. Each dot represents a single sample; the line depicts the mean. *, P < .05.
