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. 1984 Aug;4(8):1638–1640. doi: 10.1128/mcb.4.8.1638

The gene and the pseudogene for mouse p53 cellular tumor antigen are located on different chromosomes.

H H Czosnek, B Bienz, D Givol, R Zakut-Houri, D D Pravtcheva, F H Ruddle, M Oren
PMCID: PMC368959  PMID: 6387444

Abstract

The chromosomal assignments of the two genes encoding the murine p53 cellular tumor antigen were determined by using a panel of mouse-Chinese hamster somatic cell hybrid clones and a mouse p53-specific cDNA clone. One gene, probably the functional member of the family, was found to be on chromosome 11. The other gene, which is probably a processed pseudogene, was assigned to chromosome 14. The potential relevance of these findings to documented cases of chromosome 11 trisomy are also discussed.

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Selected References

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