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. 1984 Aug;4(8):1657–1660. doi: 10.1128/mcb.4.8.1657

Expression of simian virus 40 large T antigen in embryonal carcinoma cell hybrids.

A Tunnacliffe, L V Crawford, P Goodfellow
PMCID: PMC368964  PMID: 6149461

Abstract

Previous work has shown that murine embryonal carcinoma cells are refractory to infection with various viruses, including simian virus 40. Thus, large T and small t antigens, the products of the simian virus 40 early region, are not produced when the virus infects embryonal carcinoma cells, in contrast to other cell types. We show, by qualitative and quantitative analyses, that embryonal carcinoma cell hybrids, containing a simian virus 40 early region integrated into human DNA, are capable of producing viral large T antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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