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. 1984 Aug;4(8):1661–1663. doi: 10.1128/mcb.4.8.1661

Less than 40% of the simian virus 40 large T-antigen-coding sequence is required for transformation.

L Sompayrac, K J Danna
PMCID: PMC368965  PMID: 6092929

Abstract

F8dl is a simian virus 40 early-region deletion mutant that lacks the simian virus 40 DNA sequences between 0.168 and 0.424 map units. Despite this large deletion, cloned F8dl DNA transforms Fisher rat F111 cells and BALB/3T3 clone A31 mouse cells as efficiently as does cloned simian virus 40 wild-type DNA. These results indicate that less than 40% of the large T-antigen-coding sequence is required for efficient transformation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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