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The Effect of Adding LNA Directed to the Dimerization Signal of HIV-1 5′ UTR RNA
(A) LNA recognition site at the dimerization palindrome located at the loop of SL1.
(B) Native agarose gel showing 310 nt HIV-1 5′ UTR with (lane 1) and without (lane 2) LNA, monomer (Mo) and dimer (Di) labeled.
(C and D) FRET-derived histogram with Gaussian curves overlaid from labeled RNA (C) without LNA and (D) with LNA.
See also Figure S3.
