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Molecular and Cellular Biology logoLink to Molecular and Cellular Biology
. 1985 Dec;5(12):3634–3639. doi: 10.1128/mcb.5.12.3634

Structure of the rat alpha 1-acid glycoprotein gene.

Y C Liao, J M Taylor, J L Vannice, G A Clawson, E A Smuckler
PMCID: PMC369197  PMID: 2943986

Abstract

The complete nucleotide sequence of the rat alpha 1-acid glycoprotein gene has been determined from an isolated lambda recombinant bacteriophage. Southern blot analysis and DNA sequencing indicate that there is only one gene per genome; it contains six exons and is located within a 3,200-base-pair fragment starting from a TATA box and extending to the polyadenylation signal AATAAA. Transcription starts 37 base pairs upstream from the beginning of the translation codon ATG. The TATA box (TATAAA) lies 26 base pairs upstream from this site. The gene contains several potential glucocorticoid receptor-binding sites, both inside and outside the structural gene.

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Selected References

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