Table 2.
Baseline | ‘Immediate Testing’ |
||||
---|---|---|---|---|---|
OFF medication OFF stimulation | Standard STN stimulation | Combined STN+SNr stimulation | P-value | ||
Secondary endpoints | |||||
Axial UPDRS III (items 27–31) | 11.17 ± 3.56 | 9.25 ± 4.67 | 8.17 ± 4.09 | 0.041a | |
Segmental UPDRS III (items 20–26) | 38.0 ± 5.10 | 29.17 ± 6.62 | 27.58 ± 7.96 | 0.1347a | |
FOG-AC | 22.17 ± 11.74 | 16.25 ± 12.78 | 8.67 ± 10.92 | 0.0056a | |
CAPSIT [steps] | 18.5 (13–82)§ | 14.5 (8–51.5)§ | 14.5 (8.5–36)§ | 0.5488b | |
CAPSIT [time] | 12 (6.5–105)§ | 7.5 (5.5–67.5)§ | 8.5 (5–28)§ | 0.7539b | |
CAPSIT [freezing] | 0.5 (0–3)§ | 0.5 (0–3)§ | 0 (0–0.5)§ | >0.99b | |
Berg Balance Scale | 41.5 (11–56)§ | 47 (15–56)§ | 50 (9–56)§ | 0.7266b |
FOG-AC = Freezing of Gait Assessment Course.
at-Test.
bSign Test.
§Median (Min–Max).