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. 1984 Dec;4(12):2843–2850. doi: 10.1128/mcb.4.12.2843

Isolation of monoclonal antibodies specific for products of avian oncogene myb.

G I Evan, G K Lewis, J M Bishop
PMCID: PMC369296  PMID: 6084811

Abstract

We isolated a series of monoclonal antibodies which were raised against a bacterially expressed protein, bp37v-myb, and coded for by part of the avian v-myb gene. These monoclonal antibodies recognized a range of antigenic specificities on bp37v-myb, and this was reflected in their differing specificities for the gene products of the v-myb, c-myb, and E26 viral oncogenes. One monoclonal antibody recognized, in addition to the v-myb and c-myb gene products, a conserved nuclear protein found in all tested cells. We describe the characterization of these monoclonal antibodies.

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Selected References

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