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. 1991 Mar;11(3):1745–1750. doi: 10.1128/mcb.11.3.1745

Adenovirus type 5 E1A gene products act as transformation suppressors of the neu oncogene.

D H Yu 1, K Scorsone 1, M C Hung 1
PMCID: PMC369488  PMID: 1671710

Abstract

The adenovirus type 5 early region 1A (E1A) gene was introduced into neu-transformed B104-1-1 cells. Cells that expressed E1A possessed reduced transforming activity in vitro and reduced tumorigenicity in nude mice. These results demonstrate that the E1A gene products can act negatively to suppress the transformed phenotype in neu-transformed cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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