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. 1982 Nov;2(11):1399–1409. doi: 10.1128/mcb.2.11.1399

Chromosomes XIV and XVII of Saccharomyces cerevisiae constitute a single linkage group.

S Klapholz, R E Esposito
PMCID: PMC369944  PMID: 6761582

Abstract

We present several lines of evidence that chromosomes XIV and XVII of Saccharomyces cerevisiae are not independent chromosomes, but rather constitute a single linkage group. Studies which made use of a new mapping method based on the haploidization-without-recombination meiotic phenotype of the spoll mutant initially indicated that markers on chromosomes XIV and XVII were linked. Tetrad analysis was used to establish gene-gene distances, and a new chromosome XIV map incorporating markers originally assigned to chromosome XVII was derived. During the course of trisomic segregation studies, we discovered that a 2n + 2 homothallic diploid, originally believed to be tetrasomic for chromosome XVII (now XIV), carries two normal chromosome XIV homologs and two aberrant homologs which appear to be deficient for a large portion of the right arm of XIV. The previous evidence that established chromosome XVII as an independent linkage group is discussed in the light of these findings.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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