Abstract
The American Society for Microbiology (ASM) and Molecular and Cellular Biology (MCB) are issuing this Expression of Concern to alert readers to doubts about the integrity of the data in papers coauthored by Dr. Shigeaki Kato.
In 2012, ASM was notified that the University of Tokyo Institute of Molecular and Cellular Biosciences is conducting an investigation of possible scientific misconduct by Dr. Kato. Among the publications under investigation for possible data manipulation are these five MCB articles. The Expression of Concern is only for papers coauthored by Dr. Kato that have been published since 2007, in accordance with the DHHS/ORI six-year limitation on research misconduct (http://ori.dhhs.gov/sites/default/files/42_cfr_parts_50_and_93_2005.pdf).
MCB has contacted the Research Promotion Department of the University of Tokyo and asked to be informed of the findings of their ongoing investigation. Once ASM has been notified of the outcome of the investigation by the University of Tokyo, MCB will take appropriate action regarding these publications.
Corepressive Action of CBP on Androgen Receptor Transactivation in Pericentric Heterochromatin in a Drosophila Experimental Model System
Yue Zhao, Ken-ichi Takeyama, Shun Sawatsubashi, Saya Ito, Eriko Suzuki, Kaoru Yamagata, Masahiko Tanabe, Shuhei Kimura, Sally Fujiyama, Takashi Ueda, Takuya Murata, Hiroyuki Matsukawa, Yuko Shirode, Alexander P. Kouzmenko, Feng Li, Testuya Tabata, Shigeaki Kato
The Institute of Molecular and Cellular Biosciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan; Exploratory Research for Advanced Technology, Kawaguchi, Saitama, Japan; Department of Cell Biology, Key Laboratory of Cell Biology, Ministry of Public Health of China, China Medical University, Shenyang, Liaoning, People's Republic of China
Coactivation of Estrogen Receptor β by Gonadotropin-Induced Cofactor GIOT-4
Madoka Kouzu-Fujita, Yoshihiro Mezaki, Shun Sawatsubashi, Takahiro Matsumoto, Ikuko Yamaoka, Tetsu Yano, Yuji Taketani, Hirochika Kitagawa, Shigeaki Kato
Institute of Molecular and Cellular Biosciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan; Department of Obstetrics and Gynecology, University of Tokyo, Bunkyo-ku, Tokyo, Japan; ERATO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan
Vitamin K Induces Osteoblast Differentiation through Pregnane X Receptor-Mediated Transcriptional Control of the Msx2 Gene
Mamoru Igarashi, Yoshiko Yogiashi, Masatomo Mihara, Ichiro Takada, Hirochika Kitagawa, Shigeaki Kato
The Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan; ERATO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan
A Regulatory Circuit Mediating Convergence between Nurr1 Transcriptional Regulation and Wnt Signaling
Hirochika Kitagawa, William J. Ray, Helmut Glantschnig, Pascale V. Nantermet, Yuanjiang Yu, Chih-Tai Leu, Shun-ichi Harada, Shigeaki Kato, Leonard P. Freedman
Department of Molecular Endocrinology, Merck Research Laboratories, West Point, Pennsylvania; Institute of Molecular and Cellular Biosciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan; ERATO, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan
The Pituitary Function of Androgen Receptor Constitutes a Glucocorticoid Production Circuit
Junko Miyamoto, Takahiro Matsumoto, Hiroko Shiina, Kazuki Inoue, Ichiro Takada, Saya Ito, Johbu Itoh, Takeo Minematsu, Takashi Sato, Toshihiko Yanase, Hajime Nawata, Yoshiyuki R. Osamura, Shigeaki Kato
Institute of Molecular and Cellular Biosciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan; ERATO, Japan Science and Technology Agency, Kawaguchisi, Saitama, Japan; Teaching and Research Support Center and Department of Pathology, Tokai University School of Medicine, Boseidai, Isehara, Kanagawa, Japan; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan