Table 1.

Sustained pain alters functional connectivity (PAIN – REST)

	side	size (mm3)	MNI coordinates			z-stat (mean±sd)
			X	Y	Z	peak z-stat	REST	PAIN
Salience Network (SLN)
S1/M1	R	8,128	10	−40	74	5.20	0.53±1.39	2.45±1.82
Sensorimotor Network (SMN)
S1/M1	R	4,520	4	−22	52	−4.10	4.73±2.26	2.59±2.06
	L	3,880	−28	−26	58	−3.98	5.73±2.19	4.58±2.26
Dorsal Attention Network (DAN)
Cerebellum (VI l)	L	12,672	−28	−60	−24	4.05	1.18±1.56	3.00±1.43
	R	6,048	26	−52	−24	3.90	0.49±1.28	2.08±1.10
pons	R	6,048	2	−30	−40	2.99	−0.38±1.40	0.91±1.36
NRD/NCF	L	6,048	−4	−30	−16	2.92	−0.67±1.25	0.46±1.47
putamen	L	5,176	−30	−24	14	3.58	−0.65±1.44	0.87±1.07
posterior insula	L	5,176	−40	−22	12	2.67	−1.65±1.30	0.54±1.48
MCC	R	4,728	4	20	38	3.07	0.04±1.13	1.81±1.18
preSMA	R	4,728	4	2	58	3.16	−0.71±1.31	0.77±1.44
right Fronto-parietal control network (rFCN)
precuneus	L	3,264	−10	−52	60	−4.06	−1.02±1.67	−2.88±1.89
S1/M1	L	3,264	−2	−36	58	−3.19	0.46±1.39	−0.69±1.54
right (contralateral) S1/M1 seed connectivity
anterior insula	R	8,088	44	8	0	3.89	1.45±1.15	3.76±1.81
S1/M1	R	14,056	32	−28	58	−4.51	15.57±7.54	10.43±4.18
	L	20,368	−12	−38	70	−3.79	11.14±5.57	5.23±2.67