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. 1983 Jul;3(7):1204–1211. doi: 10.1128/mcb.3.7.1204

Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity.

S Smolik-Utlaut, T D Petes
PMCID: PMC370111  PMID: 6350848

Abstract

As a model system for studying the properties of mitotic recombination in the yeast Saccharomyces cerevisiae, we have examined recombination between a recombinant plasmid (introduced into the S. cerevisiae cell by transformation) and homologous chromosomal loci. The recombinant plasmids used in these experiments contained S. cerevisiae rRNA genes. We found that the frequency of integrative recombination is sensitive to small amounts of sequence heterogeneity. In addition, the frequency and specificity of these recombination events are affected by the lengths of the interacting homologous DNA sequences.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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