Table 3.
The relationship between maternal alcohol consumption in the 2nd trimester of pregnancy and child blood pressure and PWV at 9 years. Regression coefficients (CI) are from mixed-effects regression models and represent the ‘effect’ of a mother drinking alcohol vs. abstaining (n = 294 for blood pressure and n = 289 for PWV)
Mother abstained | Mother drank alcohol | Unadjusted difference | 95% CI | p | Adjusted difference | 95% CI | p | |
---|---|---|---|---|---|---|---|---|
Mean (SD) systolic blood pressure, mm Hg | 97.3 (11.9) | 97.8 (9.6) | 0.8 | −2.6, 4.3 | 0.6 | −0.3a | −3.7, 3.2 | 0.9 |
Mean (SD) diastolic blood pressure, mm Hg | 53.3 (6.7) | 53.2 (6.2) | 0.1 | −1.9, 2.2 | 0.9 | −0.4b | −2.5, 1.7 | 0.7 |
Mean (SD) carotid-femoral PWV, m/s | 5.8 (0.7) | 6.1 (0.7) | 0.3 | 0.1, 0.5 | 0.001 | 0.2c | 0.03, 0.4 | 0.02 |
Mean (SD) femoral-dorsalis pedis PWV, m/s | 7.5 (1.3) | 7.3 (1.1) | −0.2 | −0.5, 0.1 | 0.3 | −0.2c | −0.6, 0.1 | 0.2 |
Adjusted for maternal smoking in the second trimester and home ownership.
Adjusted for gestational length in weeks.
Adjusted for child age, maternal weight at the end of pregnancy and whether mother or father had tertiary education.