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. Author manuscript; available in PMC: 2014 Jun 10.
Published in final edited form as: Biomacromolecules. 2013 May 20;14(6):1961–1970. doi: 10.1021/bm400342f

Figure 7.

Figure 7

Transfection of HPMA-oligolysine-oligohistidine polyplexes in HeLa and COS-7 cells with chlorpromazine, genistein, or amiloride. (A) Transfection efficiency and (B) protein content of HeLa cells, and (C) transfection efficiency and (D) cell viability of COS-7 cells transfected with polyplexes formulated with statistical (pShi0, pShi2) or diblock (pB0, pB1) and DNA (1 μg) at N/P 5 in the presence of 10 μg/mL chlorpromazine, 50 μg/mL genistein, or 25 μg/mL amiloride under serum-free conditions. Data are presented as the mean ± S.D., n = 4, and representative of four independent experiments. (*) p < 0.05, as determined by a two-tailed, unpaired Student’s t-test with unequal variance.