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editorial

. 2013 Jan 27;4(1):1–2. doi: 10.18632/oncotarget.824

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Copyright: © 2013 McKee et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

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Above: PN1- mediated blockade of SHH downstream signaling slows cancer proliferation and neo-angiogenesis. The effect can be inhibited by MMP9. Below: whole mount prostate tissue shows that SHH staining (brown) occurs primarily in prostate tumour cells rather than normal prostate.