Table 1.
SS | LS | SL | LL | |
---|---|---|---|---|
Start weight, g | 320 ± 6 | 314 ± 7 | 321 ± 7 | 323 ± 4 |
End weight, g | 319 ± 5b | 303 ± 15b | 318 ± 9b | 267 ± 17c |
Liver weight, g | 11.0 ± 0.5 | 9.9 ± 0.9 | 10.7 ± 0.9 | 9.2 ± 1.0 |
Liver lipid, mg | 429 ± 21b | 359 ± 39b | 414 ± 37b | 322 ± 40c |
Liver glycogen, mg | 138 ± 20 | 83 ± 16 | 114 ± 33 | 104 ± 29 |
Fat depots | ||||
Inguinal, g | 3.02 ± 0.38b | 1.87 ± 0.48b | 2.51 ± 0.43b | 1.02 ± 0.13c |
Epididymal, g | 2.05 ± 0.23b | 1.84 ± 0.45b | 1.71 ± 0.34b | 0.45 ± 0.11c |
Retroperitoneal, g | 0.62 ± 0.12b | 0.63 ± 0.21b | 0.59 ± 0.17b | 0.09 ± 0.03c |
Mesenteric, g | 0.80 ± 0.18 | 0.63 ± 0.18 | 0.65 ± 0.17 | 0.38 ± 0.14 |
Serum measures | ||||
Leptin, ng/mL | 1.28 ± 0.13 | 1.40 ± 0.24 | 1.36 ± 0.11 | 0.95 ± 0.11 |
Insulin, ng/mL | 2.55 ± 0.56 | 2.29 ± 0.60 | 1.91 ± 0.55 | 1.52 ± 0.67 |
Range | 0.27–5.09 | 0.29–4.67 | 0.21–7.14 | 0.43–4.08 |
Glucose, mg/dL | 117 ± 9 | 125 ± 11 | 122 ± 16 | 116 ± 18 |
Range | 72–152 | 84–156 | 71–191 | 84–160 |
IBAT temperature, °C | ||||
Daytime temperature | 36.55 ± 0.08b | 36.51 ± 0.06b,c | 36.65 ± 0.07b,c | 36.82 ± 0.12c |
Nighttime temperature | 37.44 ± 0.01 | 37.41 ± 0.04 | 37.59 ± 0.04 | 37.70 ± 0.11 |
Data are means ± SEM for groups of 8 rats. All measures were made after 12 days of infusion.
Values for a specific parameter that do not share a common superscript are significantly different at P < .05.