Fig. 2.

Electrophysiology associated with neuron depolarization with application of 50 mm K⁺. The transmembrane potential (A) was recorded during application of K⁺, indicated by the bar. A similar voltage command protocol (B) was used during subsequent current recordings. Sequential current traces (C) were recorded during cumulative application of blockers, starting with baseline (BL), then ω-agatoxin-IVA (Aga-IVA, 200 nm), then addition of SNX-482 (200 nm), SNX-111 (200 nm), and nisoldipine (Nisold, 200 nm). Subtracted traces (D) show the current sensitive to Aga-IVA, SNX-482, SNX-111, and nisoldipine.