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. 1979 Sep;64(3):866–869. doi: 10.1172/JCI109535

Deletion of the A gamma-globin gene in G gamma-delta beta-thalassemia.

S H Orkin, B P Alter, C Altay
PMCID: PMC372193  PMID: 468997

Abstract

In an individual homozygous for G gamma-delta beta-thalassemia, a physical alteration in gamma-globin gene organization was detected by restriction enzyme mapping. The data indicated that the absence of A gamma-globin chains resulted from extension of the DNA deletion from the delta beta-globin gene region into the gamma-globin gene region rather than a functional disturbance of gamma-gene expression.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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