Fig. 3.

Mtb Dxr active site and docking results. (A) Active site of Mtb Dxr with fosmidomycin (left ligand) and NADPH (right ligand) bound (pdb 2JCZ).¹⁸ Ligands are separated by ~3.5 Å. (B) Docked O-linked ligand 4. (C) Docked amide ligand 8. Protein chain A is shown as cartoon (blue), Mn²⁺ as a sphere (pink), ligands are shown as sticks colored by atom type, protein residues as lines colored by atom type. Hydrogen atoms have been hidden for clarity.