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. 2013 Jun 3;122(5):749–758. doi: 10.1182/blood-2013-01-480129

Figure 4.

Figure 4

Monocytes from NOD-SCID mice engrafted with human AML express increased YM-1. (A) NOD-SCID mice were injected with AML cells from patients. After engraftment, bone marrow was harvested from the femurs, and the expression of YM-1 on murine monocytes (Ly6C+) was assessed by flow cytometry. (B) Increased percentage of YM-1 positive monocytes in NOD-SCID mice engrafted with human AML. NOD-SCID mice were injected with AML cells from patients. After engraftment, bone marrow was harvested from the femurs, and the percentage of YM-1+ Ly6C+ murine monocytes was assessed by flow cytometry (***P = .0001).