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Identification of inhibitors of the virulence cascade in V. cholerae. (A) The wild-type reporter strain NB39 has a high GFP/OD600 ratio when grown overnight under toxin-inducing conditions, while the isogenic ΔtoxR strain NB39 does not. (B) Funnel figure illustrating the triage process used in the screen. (C) Structures of the toxtazins.
