Table 2.
Black* (n = 962) | Nonblack* (n = 3507) | Relative Risk (95% CI) | P† | |
---|---|---|---|---|
Failed screening evaluation | 387 (40) | 999 (28) | 1.41 (1.29–1.55) | <0.001 |
HCV treatment not initiated for reason other than treatment ineligibility | 103 (11) | 245 (7) | 1.53 (1.23–1.91) | <0.001 |
Did not wish to continue | 55 (6) | 160 (5) | 1.25 (0.93–1.69) | 0.14 |
Lost to follow-up | 39 (4) | 53 (2) | 2.68 (1.79–4.03) | <0.001 |
Noncompliance | 7 (1) | 31 (1) | 0.82 (0.36–1.86) | 0.64 |
Adverse event | 2 (<1) | 1 (<1) | n/a‡ | N/a‡ |
HCV treatment ineligible§ | 284 (30) | 754 (21) | 1.37 (1.22–1.54) | <0.001 |
Abnormal hematologic value | 65 (7) | 83 (2) | 2.85 (2.08–3.92) | <0.001 |
Abnormal chemistry value | 60 (6) | 78 (2) | 2.80 (2.02–3.90) | <0.001 |
Poorly controlled diabetes mellitus | 14 (1) | 15 (0.4) | 3.40 (1.65–7.02) | <0.001 |
Clinically significant cardiac disease | 5 (0.5) | 13 (0.4) | 1.40 (0.50–3.92) | 0.52 |
Preexisting or uncontrolled medical disease‖ | 74 (8) | 196 (6) | 1.38 (1.06–1.78) | 0.02 |
Preexisting or uncontrolled psychiatric disease¶ | 41 (4) | 125 (4) | 1.20 (0.85–1.69) | 0.31 |
Recent drug or alcohol abuse | 19 (2) | 101 (3) | 0.69 (0.42–1.11) | 0.12 |
Exclusionary virology including HCV RNA not detected, non-1 HCV genotype and missing | 14 (1) | 159 (5) | 0.32 (0.19–0.55) | <0.001 |
HCV treatment ineligible for reason other than exclusionary virology | 270 (28) | 595 (17) | 1.65 (1.46–1.87) | <0.001 |
Abbreviations: CI, confidence interval; HCV, hepatitis C virus; RNA, ribonucleic acid.
Data shown are number (percentage of total number).
P values were not adjusted for multiplicity.
Chi-square calculation not performed due to small sample size.
Patients may have more than 1 reason for ineligibility.
Identified by the investigator at the time of screening; no further information describing the specific preexisting or uncontrolled medical condition(s) was available.
Clinical diagnosis or Center for Epidemiologic Studies Depression Scale score >25.