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. 2013 Feb 20;63(2):281–291. doi: 10.1136/gutjnl-2012-303207

Figure 3.

Figure 3

Mucus thickness in wild-type (WT) and interleukin 10-deficient (IL-10−/−) mice. (A) In vivo measurements of the initial mucus thickness in WT (n=7) and IL-10−/− (n=5) mice. The total mucus thickness (Total) was measured followed by aspiration of the mucus and measurement of the remaining mucus thickness (Adherent). (B) Ex vivo measurements of the increase in total mucus thickness over time in WT (n=5) and IL-10−/− (n=6) mice. (C) Number of goblet cells per upper crypt in WT (n=5) and IL-10−/− (n=5) mice.  (D) Area of the goblet cell theca in anti-MUC2C3-stained colon section of WT (n=5) and IL-10−/− (n=5) mice. Data are presented as mean±SEM, and the two-tailed Mann–Whitney U test was used to compare the mucus thickness in WT and IL-10−/− mice.