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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Leukemia. 2010 Jun 24;24(9):1555–1565. doi: 10.1038/leu.2010.142

Table 1.

Combination Index analysis of ch128.1Av combined with HXR9 at a non-constant ratio in IM-9 cells.

[ch128.1Av] nM [HXR9] µM Fa CI Description
2.5 20 0.987 0.503 Synergism
5 20 0.997 0.382 Synergism
10 20 0.980 0.551 Synergism
20 20 0.986 0.515 Synergism
30 20 0.983 0.541 Synergism
2.5 10 0.781 0.862 Moderate Synergism
5 10 0.852 0.705 Moderate Synergism
10 10 0.899 0.609 Synergism
20 10 0.906 0.764 Moderate Synergism
30 10 0.928 0.667 Synergism

Analysis was performed using the Calcusyn software (BioSoft). Fa = fraction affected as tested by the [3H]-thymidine incorporation assay, CI = combination index. Descriptions are based on CI values and the recommendations of BioSoft: < 0.1 = very strong synergism, 0.1–0.3 = strong synergism, 0.3–0.7 = synergism, 0.7–0.85 – moderate synergism, 0.85–0.9 = slight synergism.