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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Diabetologia. 2013 Mar 19;56(6):1444–1453. doi: 10.1007/s00125-013-2884-2

Fig. 6.

Fig. 6

Vitreous from PDR patients prevented spontaneous regression. The collagen sandwich tube assay was performed in 10% (vol./vol.) serum, conditions under which tubes regress spontaneously because of the combined effect of LPA produced by cells and present in serum [25]. The indicated type of vitreous was added at 12 h, and its effect determined 4 h later. Whereas the effect of NPDR and QPDR vitreous was not statistically significant, PDR vitreous prevented regression (*p<0.05 compared with no treatment). Normalised tube length is the ratio of final and initial tube lengths. Three samples of each DR stage were analysed