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FoxO1 interaction with regulatory proteins and transcription factors
| Androgen receptor (AR) | Suppression of AR transactivation |
| PPARγ | Suppression of PPARγ and PPARγ-mediated lipogenesis |
| LXRα | Suppression of RXR/LXRα-mediated activation of SREBP-1 |
| TSC2 | Akt-phosphorylated cytoplasmic FoxO1 dissociates and thereby inhibits the TSC1/TSC2 heterodimer |
| β-Catenin | Augmentation of nuclear FoxO1 signalling |
| GSK3 | Modulation of GSK3-TSC2-mTORC1 signalling |
| CRM1 | Nuclear FoxO1 export |
