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European Journal of Human Genetics logoLink to European Journal of Human Genetics
. 2013 Aug 15;21(9):1033–1034. doi: 10.1038/ejhg.2013.104

The population prevalence of Down's syndrome in England and Wales in 2011

Jianhua Wu, Joan K Morris
PMCID: PMC3746273

Correction to: European Journal of Human Genetics (2013) 21, 1016–1019; doi:10.1038/ejhg.2012.294; published online 16 January 2013

Explanation of the error

The number of babies born with Down's syndrome was incorrectly calculated in a previous paper.1 This affected the estimates of the numbers of people with Down's syndrome in England and Wales in 2011 according to age. The original estimates were 5% too high, a total population of 38 879 instead of the revised corrected number of 37 090. The formulae estimating survival rates were also revised due to corrections to the data and are included below for completeness, however these changes were small and did not alter the overall population estimates. Acknowledgement of the use of the methodology developed by de Graaf et al2 should have been included in the manuscript.

Revised survival rates

1-year survival rate=92.210/(1+exp((1948.988−year)/6.041)).

1–5 years survival rate=98.698/(1+exp((1917.438−year)/19.310)).

5–10 years survival rate=99.750/(1+exp((1900.152−year)/19.326))

The amended article appears in this issue and the html and online PDF versions have also been corrected. The authors would like to apologise for their error.

REVISED APPENDIX TABLE 4: Age distribution of people in 2011 with Down's syndrome in England and Wales

graphic file with name ejhg2013104i1.jpg

References

  1. Wu J, Morris JK.Trends in maternal age distribution and the live birth prevalence of Down's syndrome in England and Wales: 1938–2010 Eur J Hum Genet 2013. doi: 10.1038/ejhg.2012.288 [DOI] [PMC free article] [PubMed]
  2. de Graaf G, Vis JC, Haveman M, et al. Assessment of prevalence of persons with Down syndrome: a theory-based demographic model. J Appl Res Intellect Disabil. 2011;24:247–262. [Google Scholar]

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