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. 1967 Apr;1(2):430–444. doi: 10.1128/jvi.1.2.430-444.1967

Electron Microscopy of a Plant-Pathogenic Virus in the Nervous System of Its Insect Vector

Hiroyuki Hirumi a,1, Robert R Granados a, Karl Maramorosch a
PMCID: PMC375240  PMID: 5623965

Abstract

The central nervous system of wound tumor virus (WTV)-infected Agallia constricta was studied by electron microscopy to obtain information concerning the virus distribution in the nervous system. Wound tumor virions were mostly found in the cytoplasm of the ganglion cells and less frequently in the glial cells. WTV was occasionally observed in the perineurium cells, nerve axons, tracheoblasts, and lateral nerves. In the ganglion cells, virions appeared as individual isolated particles (V1), in tubular formation (V2), and occasionally in aggregates (V3). In the glial cells, the virions were mostly seen in the V3 formation, and very seldom in the V1 and V2 formations. In the perineurium cells and tracheoblasts, only small V3 formations were observed. The isolated virions were usually surrounded with polyribosomes, and often appeared around the foci of the viroplasm. Sometimes degenerating ganglion cells infected with the WTV were encountered. These damaged cells strongly indicated that WTV exerted a cytopathogenic effect on the nerve cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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