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. 1967 Aug;1(4):678–683. doi: 10.1128/jvi.1.4.678-683.1967

Nature of Hamster Complement-fixing Antibody to Adenovirus 12 Tumor Antigen

Ruth A Fugmann 1, M Michael Sigel 1
PMCID: PMC375336  PMID: 5621470

Abstract

The presence of complement-fixing (CF) antibody reactive with T antigen and with viral C antigen in hamsters bearing adenovirus 12-induced tumors has been confirmed. Antibody activity in serum obtained at a time when the host was bearing large tumors was found to be associated exclusively with 7S immunoglobulins. Two populations of 7S immunoglobulins showing CF reactivity were distinguished by electrical charge, as determined by diethylaminoethyl cellulose chromatography and immunoelectrophoresis. No antibodies of the 19S IgM type were detected in the serum of hamsters bearing large tumors.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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