AUTHOR'S CORRECTION
Volume 87, no. 10, p 5523–5539, 2013. Page 5528, Fig. 3G: We mistakenly introduced an incomplete set of data and plotted these data as percentage of NS5A-v1 (100%) which was inconsistent with Fig. 3E which was plotted as percentage of NS5A-Nim (100%). The data set presented corresponded to only one experiment, while the transactivation levels and replication efficiencies of the constructs presented in the rest of the manuscript corresponded to an average of 3 independent experiments. Therefore, we corrected Fig. 3G by inserting the complete set of data (average of 3 experiments, instead of 1 experiment) and, to be consistent with Fig. 3E, by replotting this data set using a percentage of NS5A-Nim (100%) for the replication efficiency instead of a percentage of NS5A-v1.
Fig 3.
Impact of HCV NS5A transactivation properties on replication efficiency of subgenomic HCV replicons harboring different NS5A quasispecies variants. (G) Relationship between the transcriptional activation capacities of NS5A variants and the replication efficiencies of the corresponding subgenomic replicons. Data points represent the mean transactivational capacities as a function of replication efficiencies for NS5A variants v1, v2, v3, v4, and v5 (described in the legend for Fig. 3A), labeled g, f, e, b, and a, respectively, and AR2 swapped variants v1-AR2/v5 and v5-AR2/v1 (described in the legend to Fig. 5), labeled c and d, respectively. Percentages of replication efficiencies were calculated using NS5A-Nim (g) = 100%.
In addition, the figure legend was clarified by adding the source of all constructs represented in the graph, including the two swapped chimeras. We also clarified the y and x axes and the origin of each data point by using a letter code. This letter code is explained in the corrected legend.
Figure 3G and its corrected legend should appear as shown below.