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. 1968 Oct;2(10):1102–1106. doi: 10.1128/jvi.2.10.1102-1106.1968

Target Volume Analysis of Vaccinia Virus: Influence of Virus Dispersion and Noninfectious Particles

Guillermo Contreras 1, Adela Ohlbaum 1
PMCID: PMC375442  PMID: 5723714

Abstract

These data indicate that 90% of monodisperse vaccinia virus (VV) has a D37 dose of 1.0 × 104 ± 0.2 × 104 rad when exposed to the direct effect of gamma radiation from 137Cs and 60Co sources. This D37 dose yielded a targt size of approximately 108 daltons, close to the molecular weight of VV deoxyribonucleic acid. This target corresponds to the first component of the survival curve of VV. Noninfectious virus seemed to play a role on the slope and the proportion of the survival curve second component, suggesting that multiplicity reactivation takes place.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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