Net cost and DALYs saved across 400 vaccination policies at a vaccination cost of $250. Each point represents a distinct policy combining between 0 and 90% routine childhood coverage with one-time mass vaccination of between 0 and 90% of age groups 0–5 year olds, 0–15 year olds, 0–40 year olds, or the full population. Bold diamonds indicate those policies that include a) 0–30% routine coverage, b) 30–60% routine coverage, c) 60–80% routine coverage, and d) 80–90% routine coverage. The largest policies that are very cost-effective and cost-effective are circled. Net cost and DALYs saved were discounted and summed over a 73 year period (the average life expectancy in Brazil).