Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1968 Sep;2(9):865–868. doi: 10.1128/jvi.2.9.865-868.1968

Biological and Serological Properties of Viral Particles from a Nonproducer Rat Neoplasm Induced by Murine Sarcoma Virus (Moloney)

R C Ting 1
PMCID: PMC375705  PMID: 5725318

Abstract

The viral particles present in a nonproducer rat neoplasm induced by murine sarcoma virus (MSV) Moloney isolate, as detected by electron microscopy, were found to be biologically active on normal kidney cells of random-bred Osborne-Mendel rats. The virus is designated here as MSV (0). MSV (0) differs from other pseudotypes of MSV in its host range, antigenicity, and interference pattern.

Full text

PDF
865

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dougherty R. M., Di Stefano H. S. Virus particles associated with "nonproducer" Rous sarcoma cells. Virology. 1965 Nov;27(3):351–359. doi: 10.1016/0042-6822(65)90115-7. [DOI] [PubMed] [Google Scholar]
  2. Geering G., Old L. J., Boyse E. A. Antigens of leukemias induced by naturally occurring murine leukemia virus: their relation to the antigens of gross virus and other murine leukemia viruses. J Exp Med. 1966 Oct 1;124(4):753–772. doi: 10.1084/jem.124.4.753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hartley J. W., Rowe W. P. Production of altered cell foci in tissue culture by defective Moloney sarcoma virus particles. Proc Natl Acad Sci U S A. 1966 Apr;55(4):780–786. doi: 10.1073/pnas.55.4.780. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Huebner R. J., Hartley J. W., Rowe W. P., Lane W. T., Capps W. I. Rescue of the defective genome of Moloney sarcoma virus from a noninfectious hamster tumor and the production of pseudotype sarcoma viruses with various murine leukemia viruses. Proc Natl Acad Sci U S A. 1966 Oct;56(4):1164–1169. doi: 10.1073/pnas.56.4.1164. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Huebner R. J. The murine leukemia-sarcoma virus complex. Proc Natl Acad Sci U S A. 1967 Sep;58(3):835–842. doi: 10.1073/pnas.58.3.835. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Huu Duc-Nguyen, Rosenblum E. N., Zeigel R. F. Persistent infection of a rat kidney cell line with Rauscher murine leukemia virus. J Bacteriol. 1966 Oct;92(4):1133–1140. doi: 10.1128/jb.92.4.1133-1140.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. O'Connor T. E., Fischinger P. J. Titration patterns of a murine sarcoma-leukemia virus complex: evidence for existence of competent sarcoma virions. Science. 1968 Jan 19;159(3812):325–329. doi: 10.1126/science.159.3812.325. [DOI] [PubMed] [Google Scholar]
  8. Sarma P. S., Cheong M. P., Hartley J. W., Huebner R. J. A viral interference test for mouse leukemia viruses. Virology. 1967 Sep;33(1):180–184. doi: 10.1016/0042-6822(67)90111-0. [DOI] [PubMed] [Google Scholar]
  9. Ting R. C. In vitro transformation of rat embryo cells by a murine sarcoma virus. Virology. 1966 Apr;28(4):783–785. doi: 10.1016/0042-6822(66)90272-8. [DOI] [PubMed] [Google Scholar]
  10. Valentine A. F., Bader J. P. Production of virus by mammalian cells tranformed by Rous sarcoma and murine sarcoma viruses. J Virol. 1968 Mar;2(3):224–237. doi: 10.1128/jvi.2.3.224-237.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Vogt P. K. A virus released by "nonproducing" Rous sarcoma cells. Proc Natl Acad Sci U S A. 1967 Sep;58(3):801–808. doi: 10.1073/pnas.58.3.801. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES