Table 1.
Treatments | Time (min) before and after glucose administration | |||||
---|---|---|---|---|---|---|
−30 | 0 | 30 | 90 | 150 | 210 | |
Normal animals | 78.4 ± 3.1 | 81.6 ± 3.1 | 173.2 ± 1.6 | 136.4 ± 1.8 | 99.8 ± 5.8 | 88.2 ± 2.4 |
Petroleum ether (200 mg/kg) | 75.7 ± 3.2 | 70.5 ± 4.9 | 175.6 ± 2.4 | 114.6 ± 3.4 | 106.7 ± 5.9 | 96.1 ± 1.4 |
Ethyl acetate (200 mg/kg) | 79.4 ± 2.9 | 71.4 ± 4.7 | 142.3 ± 1.8 | 117.4 ± 2.4 | 102.4 ± 3.4 | 94.5 ± 4.8 |
Ethanol (200 mg/kg) | 76.4 ± 2.6 | 72.4 ± 2.6 | 130.2 ± 1.9 | 99.1 ± 2.9 | 92.6 ± 2.3* | 84.9 ± 3.6* |
Metformin (50 mg/kg) | 77.9 ± 3.1 | 81.8 ± 2.3 | 124.1 ± 2.5 | 96.4 ± 3.2 | 89.9 ± 3.1* | 79.8 ± 2.8* |
Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to normal control group.