Abstract
Cytomegalovirus (CMV) was demonstrated to induce intrinsic interference to Newcastle disease virus (NDV) in human fibroblast cells under noncytopathic conditions. This interference is unique in that (i) cytomegalovirus is the first DNA virus demonstrated to have this property and (ii) the state of interference was transient and progressively lost as the condition of the cells changed with the development of cytopathic effect. These observations are consistent with the view that the newly formed protein responsible for interference with NDV has a limited half-life and is no longer made when cytopathic conditions are produced by CMV.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Marcus P. I., Carver D. H. Hemadsorption-negative plaque test: new assay for rubella virus revealing a unique interference. Science. 1965 Aug 27;149(3687):983–986. doi: 10.1126/science.149.3687.983. [DOI] [PubMed] [Google Scholar]
- Marcus P. I., Carver D. H. Intrinsic interference: a new type of viral interference. J Virol. 1967 Apr;1(2):334–343. doi: 10.1128/jvi.1.2.334-343.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wainwright S., Mims C. A. Plaque assay for lymphocytic choriomeningitis virus based on hemadsorption interference. J Virol. 1967 Oct;1(5):1091–1092. doi: 10.1128/jvi.1.5.1091-1092.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]