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. 1969 Jul;4(1):67–74. doi: 10.1128/jvi.4.1.67-74.1969

Early Events in Herpes Simplex Virus Infection: a Radioautographic Study

Klaus Hummeler 1, Natale Tomassini 1, Barbara Zajac 1
PMCID: PMC375839  PMID: 4309102

Abstract

The early events in herpes simplex virus infection were studied by means of radio-autography. The virus was rapidly taken up by the host cells and uncoated. Viral deoxyribonucleic acid (DNA) reached the nuclear sites of replication in 15 to 30 min after infection. The viral DNA occasionally associated with chromosomes or condensed chromatin but was more frequently found to be randomly distributed. Viral progeny appeared 3 hr after infection. These particles did not show any particular spatial relationship to the parental DNA. The morphological latent period lasted 2.5 hr.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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