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. 1969 Dec;4(6):816–822. doi: 10.1128/jvi.4.6.816-822.1969

Ribonucleic Acid and Protein Synthesis in Chick Embryo Cells Infected with Fowl Plague Virus

A Joss 1,1, S S Gandhi 1,1, A J Hay 1,2, D C Burke 1,1
PMCID: PMC375944  PMID: 16789113

Abstract

Fowl plague virus comprised four major protein components and several minor ones, two strains of the virus giving similar results. One of the components was identified as the nucleocapsid protein. Synthesis of the virion proteins could readily be detected in infected cells 3 hr after infection. The two subcellular fractions associated with viral ribonucleic acid (RNA) polymerase activity (nuclei and ribosomal pellet) were associated with the protein of the nucleocapsid and a second virion protein of unidentified function. Measurement of viral RNA and protein synthesis in cells infected with preparations of ultraviolet irradiated virus showed that the capacity to synthesise the RNA and protein species of highest molecular weight was lost most quickly, suggesting that the pieces of viral RNA function independently.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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