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. 1970 Mar;5(3):282–288. doi: 10.1128/jvi.5.3.282-288.1970

Process of Infection with Bacteriophage φX174

XXXIII. Templates for the Synthesis of Single-Stranded Deoxyribonucleic Acid

Fred Funk 1, Robert L Sinsheimer 1
PMCID: PMC376002  PMID: 5438107

Abstract

The origin of the templates for the synthesis of φX174 progeny single-stranded deoxyribonucleic acid was studied by means of the mutagenic activity associated with the decay of incorporated 3H-labeled 5-cytosine. The results indicate that the single-strand synthesis occurs in an asymmetric semiconservative manner using as template the complementary strands of the pool of replicative from molecules accumulated during the eclipse period. These complementary strands are repeatedly used as templates, and there is no detectable preferential use of complementary strand templates made early in the eclipse versus those made late.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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