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. 1970 May;5(5):541–547. doi: 10.1128/jvi.5.5.541-547.1970

Induction and Repression of l-Arabinose Isomerase in Bacteriophage-Infected Salmonella typhimurium

Maharani Chakravorty 1
PMCID: PMC376039  PMID: 4911701

Abstract

The induction of l-arabinose isomerase in Salmonella typhimurium (LT2) is repressed on infection with clear plaque forming mutants (C1 and C2) of the temperate phage P22 (C+). However, after infection with C+ leading to lysogeny, there is a temporary repression. During this period, messenger ribonucleic acid (RNA) for l-arabinose isomerase accumulates. DNA-RNA hybridization data suggest that there is transcription of host DNA during the period of repression. Interference at the level of translation might be responsible for the cessation of induced enzyme synthesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BENZER S. Induced synthesis of enzymes in bacteria analyzed at the cellular level. Biochim Biophys Acta. 1953 Jul;11(3):383–395. doi: 10.1016/0006-3002(53)90057-2. [DOI] [PubMed] [Google Scholar]
  2. CHAKRAVORTY M. INDUCTION AND REPRESSION OF L-ARABINOSE ISOMERASE IN LACTOBACILLUS PLANTARUM. Biochim Biophys Acta. 1964 Apr 6;85:152–161. doi: 10.1016/0926-6569(64)90175-0. [DOI] [PubMed] [Google Scholar]
  3. Cohen L. W., Levine M. Detection of proteins synthesized during the establishment of lysogeny with phage P22. Virology. 1966 Feb;28(2):208–213. doi: 10.1016/0042-6822(66)90144-9. [DOI] [PubMed] [Google Scholar]
  4. Gillespie D., Spiegelman S. A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane. J Mol Biol. 1965 Jul;12(3):829–842. doi: 10.1016/s0022-2836(65)80331-x. [DOI] [PubMed] [Google Scholar]
  5. Howes W. V. Protein synthesis in Escherichia coli: a phage-mediated interruption of translation. Biochim Biophys Acta. 1965 Aug 10;103(4):711–713. doi: 10.1016/0005-2787(65)90095-x. [DOI] [PubMed] [Google Scholar]
  6. LEIVE L. A NONSPECIFIC INCREASE IN PERMEABILITY IN ESCHERICHIA COLI PRODUCED BY EDTA. Proc Natl Acad Sci U S A. 1965 Apr;53:745–750. doi: 10.1073/pnas.53.4.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. LEVIN A. P., BURTON K. Inhibition of enzyme formation following infection of Escherichia coli with phage T2r. J Gen Microbiol. 1961 Jun;25:307–314. doi: 10.1099/00221287-25-2-307. [DOI] [PubMed] [Google Scholar]
  8. LEVINE M. Effect of mitomycin C on interactions between temperate phages and bacteria. Virology. 1961 Apr;13:493–499. doi: 10.1016/0042-6822(61)90280-x. [DOI] [PubMed] [Google Scholar]
  9. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  10. Rouvière J., Wyngaarden J., Cantoni J., Gros F., Kepes A. Effect of T4 infection on messenger RNA synthesis in Escherichia coli. Biochim Biophys Acta. 1968 Aug 23;166(1):94–114. doi: 10.1016/0005-2787(68)90494-2. [DOI] [PubMed] [Google Scholar]
  11. SMITH H. O., LEVINE M. THE SYNTHESIS OF PHAGE AND HOST DNA IN THE ESTABLISHMENT OF LYSOGENY. Virology. 1965 Apr;25:585–590. doi: 10.1016/0042-6822(65)90086-3. [DOI] [PubMed] [Google Scholar]
  12. SMITH H. O., LEVINE M. TWO SEQUENTIAL REPRESSIONS OF DNA SYNTHESIS IN THE ESTABLISHMENT OF LYSOGENY BY PHAGE P22 AND ITS MUTANTS. Proc Natl Acad Sci U S A. 1964 Aug;52:356–363. doi: 10.1073/pnas.52.2.356. [DOI] [PMC free article] [PubMed] [Google Scholar]

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